Saikosaponin D Inhibits Proliferation and Promotes Apoptosis Through Activation of MKK4–JNK Signaling Pathway in Pancreatic Cancer Cells

INTRODUCTION: Pancreatic cancer remains one of the most lethal malignancies and has few treatment options. Saikosaponin D (SSD), a major bioactive triterpene saponin isolated from Bupleurum chinense, has been reported to exert cytotoxicity properties toward many cancer cells. However, the effects of...

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Detalles Bibliográficos
Autores principales: Lai, Mengru, Ge, Yuqing, Chen, Meng, Sun, Siya, Chen, Jianzhen, Cheng, Rubin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522527/
https://www.ncbi.nlm.nih.gov/pubmed/33061432
http://dx.doi.org/10.2147/OTT.S263322

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522527/
https://www.ncbi.nlm.nih.gov/pubmed/33061432
http://dx.doi.org/10.2147/OTT.S263322

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