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Saikosaponin D Inhibits Proliferation and Promotes Apoptosis Through Activation of MKK4–JNK Signaling Pathway in Pancreatic Cancer Cells
INTRODUCTION: Pancreatic cancer remains one of the most lethal malignancies and has few treatment options. Saikosaponin D (SSD), a major bioactive triterpene saponin isolated from Bupleurum chinense, has been reported to exert cytotoxicity properties toward many cancer cells. However, the effects of...
Autores principales: | Lai, Mengru, Ge, Yuqing, Chen, Meng, Sun, Siya, Chen, Jianzhen, Cheng, Rubin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522527/ https://www.ncbi.nlm.nih.gov/pubmed/33061432 http://dx.doi.org/10.2147/OTT.S263322 |
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