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Co-expressing LRP6 With Anti-CD19 CAR-T Cells for Improved Therapeutic Effect Against B-ALL

BACKGROUND: Cellular immunotherapies, such as chimeric antigen receptor modified-T cell (CAR-T) therapy, offers excellent potential for tumor treatment. The memory phenotype of CAR-T has been correlated positively with a therapeutic effect on and prognosis of cancer. METHOD: The proliferation rates...

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Detalles Bibliográficos
Autores principales: He, Ping, Tan, Zhongqiu, Wei, Zhongheng, Wan, Cheng-Liang, Yang, Shan-Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522530/
https://www.ncbi.nlm.nih.gov/pubmed/33042788
http://dx.doi.org/10.3389/fonc.2020.01346