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Improving the EMA Binding Test by Using Commercially Available Fluorescent Beads

Hereditary spherocytosis (HS) is a common anemia caused by germline mutations in red blood cell cytoskeleton proteins. The flow cytometry-based eosin-5′-maleimide (EMA) binding test is most frequently employed for reliable diagnostics. To perform this test, a number of healthy and ideally also age-m...

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Detalles Bibliográficos
Autores principales: Glenthøj, Andreas, Sharfo, Alaa, Brieghel, Christian, Nardo-Marino, Amina, Birgens, Henrik, Petersen, Jesper Brix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522531/
https://www.ncbi.nlm.nih.gov/pubmed/33041866
http://dx.doi.org/10.3389/fphys.2020.569289