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Divergent Synthesis of Novel Cylindrocyclophanes that Inhibit Methicillin‐Resistant Staphylococcus aureus (MRSA)

The cylindrocyclophanes are a family of macrocyclic natural products reported to exhibit antibacterial activity. Little is known about the structural basis of this activity due to the challenges associated with their synthesis or isolation. We hypothesised that structural modification of the cylindr...

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Detalles Bibliográficos
Autores principales: Freudenreich, Julien J., Bartlett, Sean, Robertson, Naomi S., Kidd, Sarah L., Forrest, Suzie, Sore, Hannah F., Galloway, Warren R. J. D., Welch, Martin, Spring, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522682/
https://www.ncbi.nlm.nih.gov/pubmed/32424962
http://dx.doi.org/10.1002/cmdc.202000179