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New variants in NLRP3 inflammasome genes increase risk for asthma and Blomia tropicalis-induced allergy in a Brazilian population

Atopic asthma is a chronic lung disease of lower airways caused mainly due to action of T-helper (Th) 2 type cytokines, eosinophilic inflammation, mucus hypersecretion and airway remodelling. Interleukin (IL)-33 increases type 2 immunity polarization in airway playing critical role in eosinophilic a...

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Detalles Bibliográficos
Autores principales: Queiroz, Gerson de A., da Silva, Raimon R., Pires, Anaque de O., Costa, Ryan dos S., Alcântara-Neves, Neuza M., da Silva, Thiago M., Barreto, Mauricio L., Oliveira, Sergio C., Figueirêdo, Camila A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522708/
https://www.ncbi.nlm.nih.gov/pubmed/33015616
http://dx.doi.org/10.1016/j.cytox.2020.100032