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Skin α-Synuclein Aggregation Seeding Activity as a Novel Biomarker for Parkinson Disease
IMPORTANCE: Deposition of the pathological α-synuclein (αSyn(P)) in the brain is the hallmark of synucleinopathies, including Parkinson disease (PD), Lewy body dementia (LBD), and multiple system atrophy (MSA). Whether real-time quaking-induced conversion (RT-QuIC) and protein misfolding cyclic ampl...
Autores principales: | , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Medical Association
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522783/ https://www.ncbi.nlm.nih.gov/pubmed/32986090 http://dx.doi.org/10.1001/jamaneurol.2020.3311 |