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Skin α-Synuclein Aggregation Seeding Activity as a Novel Biomarker for Parkinson Disease

IMPORTANCE: Deposition of the pathological α-synuclein (αSyn(P)) in the brain is the hallmark of synucleinopathies, including Parkinson disease (PD), Lewy body dementia (LBD), and multiple system atrophy (MSA). Whether real-time quaking-induced conversion (RT-QuIC) and protein misfolding cyclic ampl...

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Detalles Bibliográficos
Autores principales:	Wang, Zerui, Becker, Katelyn, Donadio, Vincenzo, Siedlak, Sandra, Yuan, Jue, Rezaee, Masih, Incensi, Alex, Kuzkina, Anastasia, Orrú, Christina D., Tatsuoka, Curtis, Liguori, Rocco, Gunzler, Steven A., Caughey, Byron, Jimenez-Capdeville, Maria E., Zhu, Xiongwei, Doppler, Kathrin, Cui, Li, Chen, Shu G., Ma, Jiyan, Zou, Wen-Quan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Medical Association 2020
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522783/ https://www.ncbi.nlm.nih.gov/pubmed/32986090 http://dx.doi.org/10.1001/jamaneurol.2020.3311

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