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Synthesis and evaluation of novel 2,4-disubstituted arylthiazoles against T. brucei

The design, synthesis and pharmacological evaluation of the 4-substituted-2-[3-(adamant-1-yl)-4-fluorophenyl]thiazoles 1a–j, the 4-substituted-2-[4-(adamant-1-yl)phenyl]thiazoles 2a–h, the 2-substituted-4-[4-(adamant-1-yl)phenyl]thiazoles 3a–e, the N-substituted 2-phenylthiazol-4-ethylamides 4a, b a...

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Detalles Bibliográficos
Autores principales: Georgiadis, Markos-Orestis, Kourbeli, Violeta, Papanastasiou, Ioannis P., Tsotinis, Andrew, Taylor, Martin C., Kelly, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522794/
https://www.ncbi.nlm.nih.gov/pubmed/33479605
http://dx.doi.org/10.1039/c9md00478e