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In silico identification and validation of inhibitors of the interaction between neuropilin receptor 1 and SARS-CoV-2 Spike protein

Neuropilin-1 (NRP-1) is a multifunctional transmembrane receptor for ligands that affect developmental axonal growth and angiogenesis. In addition to a role in cancer, NRP-1 is a reported entry point for several viruses, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cau...

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Detalles Bibliográficos
Autores principales: Perez-Miller, Samantha, Patek, Marcel, Moutal, Aubin, Cabel, Carly R., Thorne, Curtis A., Campos, Samuel K., Khanna, Rajesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523098/
https://www.ncbi.nlm.nih.gov/pubmed/32995772
http://dx.doi.org/10.1101/2020.09.22.308783