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SARS-CoV-2 Nsp1 suppresses host but not viral translation through a bipartite mechanism

The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a highly contagious virus that underlies the current COVID-19 pandemic. SARS-CoV-2 is thought to disable various features of host immunity and cellular defense. The SARS-CoV-2 nonstructural protein 1 (Nsp1) is known to inhibit host...

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Detalles Bibliográficos
Autores principales: Shi, Ming, Wang, Longfei, Fontana, Pietro, Vora, Setu, Zhang, Ying, Fu, Tian-Min, Lieberman, Judy, Wu, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523103/
https://www.ncbi.nlm.nih.gov/pubmed/32995777
http://dx.doi.org/10.1101/2020.09.18.302901