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Fixed single-cell RNA sequencing for understanding virus infection and host response

Single-cell transcriptomic studies that require intracellular protein staining, rare cell sorting, or inactivation of infectious pathogens are severely limited because current high-throughput RNA sequencing methods are incompatible with paraformaldehyde treatment, a common tissue and cell fixation a...

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Detalles Bibliográficos
Autores principales: Van Phan, Hoang, van Gent, Michiel, Drayman, Nir, Basu, Anindita, Gack, Michaela U., Tay, Savaş
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523121/
https://www.ncbi.nlm.nih.gov/pubmed/32995793
http://dx.doi.org/10.1101/2020.09.17.302232