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SARS-CoV-2 antibody signatures robustly predict diverse antiviral functions relevant for convalescent plasma therapy

Convalescent plasma has emerged as a promising COVID-19 treatment. However, the humoral factors that contribute to efficacy are poorly understood. This study functionally and phenotypically profiled plasma from eligible convalescent donors. In addition to viral neutralization, convalescent plasma co...

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Detalles Bibliográficos
Autores principales: Natarajan, Harini, Crowley, Andrew R., Butler, Savannah E., Xu, Shiwei, Weiner, Joshua A., Bloch, Evan M., Littlefield, Kirsten, Wieland-Alter, Wendy, Connor, Ruth I., Wright, Peter F., Benner, Sarah E., Bonny, Tania S., Laeyendecker, Oliver, Sullivan, David, Shoham, Shmuel, Quinn, Thomas C., Larman, H. Benjamin, Casadevall, Arturo, Pekosz, Andrew, Redd, Andrew D., Tobian, Aaron A.R., Ackerman, Margaret E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523138/
https://www.ncbi.nlm.nih.gov/pubmed/32995801
http://dx.doi.org/10.1101/2020.09.16.20196154