JIB-04 has broad-spectrum antiviral activity and inhibits SARS-CoV-2 replication and coronavirus pathogenesis

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Pathogenic coronaviruses represent a major threat to global public health. Here, using a recombinant reporter virus-based compound screening approach, we identified several small-molecule inhibitors that potently block the replication of the newly emerged severe acute respiratory syndrome virus 2 (S...

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Detalles Bibliográficos
Autores principales: Son, Juhee, Huang, Shimeng, Zeng, Qiru, Bricker, Traci L., Case, James Brett, Zhou, Jinzhu, Zang, Ruochen, Liu, Zhuoming, Chang, Xinjian, Harastani, Houda H., Chen, Lu, Castro, Maria Florencia Gomez, Zhao, Yongxiang, Kohio, Hinissan P., Hou, Gaopeng, Fan, Baochao, Niu, Beibei, Guo, Rongli, Rothlauf, Paul W., Bailey, Adam L., Wang, Xin, Shi, Pei-Yong, Martinez, Elisabeth D., Whelan, Sean P.J., Diamond, Michael S., Boon, Adrianus C.M., Li, Bin, Ding, Siyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523209/
https://www.ncbi.nlm.nih.gov/pubmed/32995798
http://dx.doi.org/10.1101/2020.09.24.312165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523209/
https://www.ncbi.nlm.nih.gov/pubmed/32995798
http://dx.doi.org/10.1101/2020.09.24.312165

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