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The Role of Lipids in the Initiation of α-Synuclein Misfolding

The aggregation of α-synuclein (α-syn) is inseparably connected to Parkinson’s disease (PD). It is now well-established that certain forms of α-syn aggregates, oligomers and fibrils, can exert neurotoxicity in synucleinopathies. With the exception of rare familial forms, the vast majority of PD case...

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Detalles Bibliográficos
Autores principales: Kiechle, Martin, Grozdanov, Veselin, Danzer, Karin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523214/
https://www.ncbi.nlm.nih.gov/pubmed/33042996
http://dx.doi.org/10.3389/fcell.2020.562241