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GSK-3β mediates the effects of HNF-1β overexpression in ovarian clear cell carcinoma

Deubiquitinase USP28 is a target gene of the transcription factor HNF1 homeobox β (HNF-1β), which promotes the survival of ovarian clear cell carcinoma (OCCC) cell lines. However, the pharmacological inhibition of HNF-1β can cause several adverse effects as it is abundantly expressed in numerous org...

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Detalles Bibliográficos
Autores principales: Kawahara, Naoki, Mizutani, Ayano, Matsubara, Sho, Takeda, Yoshinori, Kobayashi, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523276/
https://www.ncbi.nlm.nih.gov/pubmed/33005248
http://dx.doi.org/10.3892/etm.2020.9250