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Single-cell transcriptome analysis of tumor and stromal compartments of pancreatic ductal adenocarcinoma primary tumors and metastatic lesions

BACKGROUND: Solid tumors such as pancreatic ductal adenocarcinoma (PDAC) comprise not just tumor cells but also a microenvironment with which the tumor cells constantly interact. Detailed characterization of the cellular composition of the tumor microenvironment is critical to the understanding of t...

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Detalles Bibliográficos
Autores principales: Lin, Wei, Noel, Pawan, Borazanci, Erkut H., Lee, Jeeyun, Amini, Albert, Han, In Woong, Heo, Jin Seok, Jameson, Gayle S., Fraser, Cory, Steinbach, Margaux, Woo, Yanghee, Fong, Yuman, Cridebring, Derek, Von Hoff, Daniel D., Park, Joon Oh, Han, Haiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523332/
https://www.ncbi.nlm.nih.gov/pubmed/32988401
http://dx.doi.org/10.1186/s13073-020-00776-9