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Ibrutinib in B-cell lymphoma: single fighter might be enough?

BACKGROUND: In recent years, the B cell receptor (BCR) signaling pathway has become a “hot point” because it plays a critical role in B-cell proliferation and function. Bruton’s tyrosine kinase (BTK) is overexpressed in many subtypes of B-cell lymphoma as a downstream kinase in the BCR signaling pat...

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Detalles Bibliográficos
Autores principales: Xue, Chao, Wang, Xin, Zhang, Lingyan, Qu, Qingyuan, Zhang, Qian, Jiang, Yujie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523373/
https://www.ncbi.nlm.nih.gov/pubmed/33005100
http://dx.doi.org/10.1186/s12935-020-01518-y