pH-responsive and hyaluronic acid-functionalized metal–organic frameworks for therapy of osteoarthritis

Drug therapy of osteoarthritis (OA) is limited by the short retention and lacking of stimulus-responsiveness after intra-articular (IA) injection. The weak acid microenvironment in joint provides a potential trigger for controlled drug release systems in the treatment of OA. Herein, we developed an...

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Detalles Bibliográficos
Autores principales: Xiong, Feng, Qin, Zainen, Chen, Haimin, Lan, Qiumei, Wang, Zetao, Lan, Nihan, Yang, Yuan, Zheng, Li, Zhao, Jinmin, Kai, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523381/
https://www.ncbi.nlm.nih.gov/pubmed/32993662
http://dx.doi.org/10.1186/s12951-020-00694-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523381/
https://www.ncbi.nlm.nih.gov/pubmed/32993662
http://dx.doi.org/10.1186/s12951-020-00694-3

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