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FadA promotes DNA damage and progression of Fusobacterium nucleatum-induced colorectal cancer through up-regulation of chk2

BACKGROUND: Globally, colorectal cancer (CRC) affects more than 1 million people each year. In addition to non-modifiable and other environmental risk factors, Fusobacterium nucleatum infection has been linked to CRC recently. In this study, we explored mechanisms underlying the role of Fusobacteriu...

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Detalles Bibliográficos
Autores principales: Guo, Pin, Tian, Zibin, Kong, Xinjuan, Yang, Lin, Shan, Xinzhi, Dong, Bingzi, Ding, Xueli, Jing, Xue, Jiang, Chen, Jiang, Na, Yu, Yanan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523382/
https://www.ncbi.nlm.nih.gov/pubmed/32993749
http://dx.doi.org/10.1186/s13046-020-01677-w