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Bacterial Interference With Lactate Dehydrogenase Assay Leads to an Underestimation of Cytotoxicity

Models to study host-pathogen interactions in vitro are an important tool for investigating the infectious disease process and evaluating the efficacy of antimicrobial compounds. In these models, the viability of mammalian cells is often determined using the lactate dehydrogenase (LDH) cytotoxicity...

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Detalles Bibliográficos
Autores principales: Van den Bossche, Sara, Vandeplassche, Eva, Ostyn, Lisa, Coenye, Tom, Crabbé, Aurélie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523407/
https://www.ncbi.nlm.nih.gov/pubmed/33042868
http://dx.doi.org/10.3389/fcimb.2020.00494