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Multi-Cell Type Glioblastoma Tumor Spheroids for Evaluating Sub-Population-Specific Drug Response

Glioblastoma (GBM) is a lethal, incurable form of cancer in the brain. Even with maximally aggressive surgery and chemoradiotherapy, median patient survival is 14.5 months. These tumors infiltrate normal brain tissue, are surgically incurable, and universally recur. GBMs are characterized by genetic...

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Detalles Bibliográficos
Autores principales: Sivakumar, Hemamylammal, Devarasetty, Mahesh, Kram, David E., Strowd, Roy E., Skardal, Aleksander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523412/
https://www.ncbi.nlm.nih.gov/pubmed/33042963
http://dx.doi.org/10.3389/fbioe.2020.538663