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Multi-Cell Type Glioblastoma Tumor Spheroids for Evaluating Sub-Population-Specific Drug Response
Glioblastoma (GBM) is a lethal, incurable form of cancer in the brain. Even with maximally aggressive surgery and chemoradiotherapy, median patient survival is 14.5 months. These tumors infiltrate normal brain tissue, are surgically incurable, and universally recur. GBMs are characterized by genetic...
Autores principales: | Sivakumar, Hemamylammal, Devarasetty, Mahesh, Kram, David E., Strowd, Roy E., Skardal, Aleksander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523412/ https://www.ncbi.nlm.nih.gov/pubmed/33042963 http://dx.doi.org/10.3389/fbioe.2020.538663 |
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