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Using multiple measurements of tissue to estimate subject- and cell-type-specific gene expression

MOTIVATION: Patterns of gene expression, quantified at the level of tissue or cells, can inform on etiology of disease. There are now rich resources for tissue-level (bulk) gene expression data, which have been collected from thousands of subjects, and resources involving single-cell RNA-sequencing...

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Detalles Bibliográficos
Autores principales: Wang, Jiebiao, Devlin, Bernie, Roeder, Kathryn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523682/
https://www.ncbi.nlm.nih.gov/pubmed/31400192
http://dx.doi.org/10.1093/bioinformatics/btz619