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Review of rationale and progress toward targeting cyclin-dependent kinase 2 (CDK2) for male contraception(†)
Cyclin-dependent kinase 2 (CDK2) is a member of the larger cell cycle regulating CDK family of kinases, activated by binding partner cyclins as its name suggests. Despite its canonical role in mitosis, CDK2 knockout mice are viable but sterile, suggesting compensatory mechanisms for loss of CDK2 in...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523694/ https://www.ncbi.nlm.nih.gov/pubmed/32543655 http://dx.doi.org/10.1093/biolre/ioaa107 |