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Alignment-Integrated Reconstruction of Ancestral Sequences Improves Accuracy

Ancestral sequence reconstruction (ASR) uses an alignment of extant protein sequences, a phylogeny describing the history of the protein family and a model of the molecular-evolutionary process to infer the sequences of ancient proteins, allowing researchers to directly investigate the impact of seq...

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Detalles Bibliográficos
Autores principales: Aadland, Kelsey, Kolaczkowski, Bryan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523730/
https://www.ncbi.nlm.nih.gov/pubmed/32785673
http://dx.doi.org/10.1093/gbe/evaa164