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Alignment-Integrated Reconstruction of Ancestral Sequences Improves Accuracy
Ancestral sequence reconstruction (ASR) uses an alignment of extant protein sequences, a phylogeny describing the history of the protein family and a model of the molecular-evolutionary process to infer the sequences of ancient proteins, allowing researchers to directly investigate the impact of seq...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523730/ https://www.ncbi.nlm.nih.gov/pubmed/32785673 http://dx.doi.org/10.1093/gbe/evaa164 |