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Discovery and Validation of Urinary Molecular Signature of Early Sepsis

OBJECTIVES: Identify alterations in gene expression unique to systemic and kidney-specific pathophysiologic processes using whole-genome analyses of RNA isolated from the urinary cells of sepsis patients. DESIGN: Prospective cohort study. SETTING: Quaternary care academic hospital. PATIENTS: A total...

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Detalles Bibliográficos
Autores principales: Bandyopadhyay, Sabyasachi, Lysak, Nicholas, Adhikari, Lasith, Velez, Laura M., Sautina, Larysa, Mohandas, Rajesh, Lopez, Maria-Cecilia, Ungaro, Ricardo, Peng, Ying-Chih, Kadri, Ferdous, Efron, Philip, Brakenridge, Scott, Moldawer, Lyle, Moore, Frederick, Baker, Henry V., Segal, Mark S., Ozrazgat-Baslanti, Tezcan, Rashidi, Parisa, Bihorac, Azra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523873/
https://www.ncbi.nlm.nih.gov/pubmed/33063018
http://dx.doi.org/10.1097/CCE.0000000000000195