Lower DNA methylation levels in CpG island shores of CR1, CLU, and PICALM in the blood of Japanese Alzheimer’s disease patients

The aim of the present study was to (1) investigate the relationship between late-onset Alzheimer’s disease (AD) and DNA methylation levels in six of the top seven AD-associated genes identified through a meta-analysis of recent genome wide association studies, APOE, BIN1, PICALM, CR1, CLU, and ABCA...

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Detalles Bibliográficos
Autores principales: Mitsumori, Risa, Sakaguchi, Kazuya, Shigemizu, Daichi, Mori, Taiki, Akiyama, Shintaro, Ozaki, Kouichi, Niida, Shumpei, Shimoda, Nobuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523949/
https://www.ncbi.nlm.nih.gov/pubmed/32991610
http://dx.doi.org/10.1371/journal.pone.0239196

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523949/
https://www.ncbi.nlm.nih.gov/pubmed/32991610
http://dx.doi.org/10.1371/journal.pone.0239196

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