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Lower DNA methylation levels in CpG island shores of CR1, CLU, and PICALM in the blood of Japanese Alzheimer’s disease patients
The aim of the present study was to (1) investigate the relationship between late-onset Alzheimer’s disease (AD) and DNA methylation levels in six of the top seven AD-associated genes identified through a meta-analysis of recent genome wide association studies, APOE, BIN1, PICALM, CR1, CLU, and ABCA...
Autores principales: | Mitsumori, Risa, Sakaguchi, Kazuya, Shigemizu, Daichi, Mori, Taiki, Akiyama, Shintaro, Ozaki, Kouichi, Niida, Shumpei, Shimoda, Nobuyoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523949/ https://www.ncbi.nlm.nih.gov/pubmed/32991610 http://dx.doi.org/10.1371/journal.pone.0239196 |
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