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Polydopamine-assisted PDGF-BB immobilization on PLGA fibrous substrate enhances wound healing via regulating anti-inflammatory and cytokine secretion

Platelet-derived growth factor-bb (PDGF-BB) is a potent chemokine and mitogen for fibroblasts, keratinocytes, and vascular endothelium in the injured area, believed to be effective in wound healing. However, the short half-life of PDGF-BB and its rapid release from the wound surface limited its effi...

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Detalles Bibliográficos
Autores principales: Yang, Xiao, Zhan, Peng, Wang, Xiuyan, Zhang, Qiushuang, Zhang, Yi, Fan, Haitao, Li, Ranwei, Zhang, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523965/
https://www.ncbi.nlm.nih.gov/pubmed/32991599
http://dx.doi.org/10.1371/journal.pone.0239366