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Polydopamine-assisted PDGF-BB immobilization on PLGA fibrous substrate enhances wound healing via regulating anti-inflammatory and cytokine secretion
Platelet-derived growth factor-bb (PDGF-BB) is a potent chemokine and mitogen for fibroblasts, keratinocytes, and vascular endothelium in the injured area, believed to be effective in wound healing. However, the short half-life of PDGF-BB and its rapid release from the wound surface limited its effi...
Autores principales: | Yang, Xiao, Zhan, Peng, Wang, Xiuyan, Zhang, Qiushuang, Zhang, Yi, Fan, Haitao, Li, Ranwei, Zhang, Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523965/ https://www.ncbi.nlm.nih.gov/pubmed/32991599 http://dx.doi.org/10.1371/journal.pone.0239366 |
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