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Refining surgical models of osteoarthritis in mice and rats alters pain phenotype but not joint pathology
The relationship between osteoarthritis (OA) structural change and pain is complex. Surgical models of OA in rodents are often rapid in onset, limiting mechanistic utility and translational validity. We aimed to investigate the effect of refining surgical small rodent models of OA on both joint path...
Autores principales: | Gowler, Peter R. W., Mapp, Paul I., Burston, James J., Shahtaheri, Mohsen, Walsh, David A., Chapman, Victoria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523978/ https://www.ncbi.nlm.nih.gov/pubmed/32991618 http://dx.doi.org/10.1371/journal.pone.0239663 |
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