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Effects of an anti-IGF-1 receptor monoclonal antibody on laminitis induced by prolonged hyperinsulinaemia in Standardbred horses

Currently, there are no registered veterinary drugs for the treatment of endocrinopathic equine laminitis, and although this form of the disease is known to be caused by prolonged hyperinsulinaemia, the mechanism of insulin toxicity is unclear. One possibility is that high concentrations of insulin...

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Detalles Bibliográficos
Autores principales: Rahnama, Samira, Vathsangam, Niveditha, Spence, Robert, Medina-Torres, Carlos E., Pollitt, Christopher C., de Laat, Melody A., Bailey, Simon R., Sillence, Martin N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524003/
https://www.ncbi.nlm.nih.gov/pubmed/32991593
http://dx.doi.org/10.1371/journal.pone.0239261