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Effects of an anti-IGF-1 receptor monoclonal antibody on laminitis induced by prolonged hyperinsulinaemia in Standardbred horses
Currently, there are no registered veterinary drugs for the treatment of endocrinopathic equine laminitis, and although this form of the disease is known to be caused by prolonged hyperinsulinaemia, the mechanism of insulin toxicity is unclear. One possibility is that high concentrations of insulin...
Autores principales: | Rahnama, Samira, Vathsangam, Niveditha, Spence, Robert, Medina-Torres, Carlos E., Pollitt, Christopher C., de Laat, Melody A., Bailey, Simon R., Sillence, Martin N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524003/ https://www.ncbi.nlm.nih.gov/pubmed/32991593 http://dx.doi.org/10.1371/journal.pone.0239261 |
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