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Dynamical mesoscale model of absence seizures in genetic models

A mesoscale network model is proposed for the development of spike and wave discharges (SWDs) in the cortico-thalamo-cortical (C-T-C) circuit. It is based on experimental findings in two genetic models of childhood absence epilepsy–rats of WAG/Rij and GAERS strains. The model is organized hierarchic...

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Detalles Bibliográficos
Autores principales: Medvedeva, T. M., Sysoeva, M. V., Lüttjohann, A., van Luijtelaar, G., Sysoev, I. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524004/
https://www.ncbi.nlm.nih.gov/pubmed/32991590
http://dx.doi.org/10.1371/journal.pone.0239125