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The relative contributions of infectious and mitotic spread to HTLV-1 persistence

Human T-lymphotropic virus type-1 (HTLV-1) persists within hosts via infectious spread (de novo infection) and mitotic spread (infected cell proliferation), creating a population structure of multiple clones (infected cell populations with identical genomic proviral integration sites). The relative...

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Detalles Bibliográficos
Autores principales: Laydon, Daniel J., Sunkara, Vikram, Boelen, Lies, Bangham, Charles R. M., Asquith, Becca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524007/
https://www.ncbi.nlm.nih.gov/pubmed/32941445
http://dx.doi.org/10.1371/journal.pcbi.1007470