Phosphodiesterase 5 (PDE5) restricts intracellular cGMP accumulation during enterotoxigenic Escherichia coli infection

Diarrhea caused by enterotoxigenic Escherichia coli (ETEC) has a continuing impact on residents and travelers in underdeveloped countries. Both heat-labile (LT) and heat-stable (ST) enterotoxins contribute to pathophysiology via induction of cyclic nucleotide synthesis, and previous investigations f...

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Detalles Bibliográficos
Autores principales: Foulke-Abel, Jennifer, Yu, Huimin, Sunuwar, Laxmi, Lin, Ruxian, Fleckenstein, James M., Kaper, James B., Donowitz, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research paper/Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524150/
https://www.ncbi.nlm.nih.gov/pubmed/32378997
http://dx.doi.org/10.1080/19490976.2020.1752125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524150/
https://www.ncbi.nlm.nih.gov/pubmed/32378997
http://dx.doi.org/10.1080/19490976.2020.1752125

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