Continuous pre- and post-transplant exposure to a disease-associated gut microbiome promotes hyper-acute graft-versus-host disease in wild-type mice

OBJECTIVE: The gut microbiome plays a key role in the development of acute graft-versus-host disease (GVHD) following allogeneic hematopoietic stem cell transplantation. Here we investigate the individual contribution of the pre- and post-transplant gut microbiome to acute GVHD using a well-studied...

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Detalles Bibliográficos
Autores principales: Bowerman, Kate L, Varelias, Antiopi, Lachner, Nancy, Kuns, Rachel D, Hill, Geoffrey R, Hugenholtz, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research Paper/Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524395/
https://www.ncbi.nlm.nih.gov/pubmed/31928131
http://dx.doi.org/10.1080/19490976.2019.1705729

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524395/
https://www.ncbi.nlm.nih.gov/pubmed/31928131
http://dx.doi.org/10.1080/19490976.2019.1705729

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