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A circuit mechanism for decision-making biases and NMDA receptor hypofunction

Decision-making biases can be features of normal behaviour, or deficits underlying neuropsychiatric symptoms. We used behavioural psychophysics, spiking-circuit modelling and pharmacological manipulations to explore decision-making biases during evidence integration. Monkeys showed a pro-variance bi...

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Detalles Bibliográficos
Autores principales: Cavanagh, Sean Edward, Lam, Norman H, Murray, John D, Hunt, Laurence Tudor, Kennerley, Steven Wayne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524553/
https://www.ncbi.nlm.nih.gov/pubmed/32988455
http://dx.doi.org/10.7554/eLife.53664