Endothelial TGF-β signaling instructs smooth muscle cell development in the cardiac outflow tract

The development of the cardiac outflow tract (OFT), which connects the heart to the great arteries, relies on a complex crosstalk between endothelial (ECs) and smooth muscle (SMCs) cells. Defects in OFT development can lead to severe malformations, including aortic aneurysms, which are frequently as...

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Detalles Bibliográficos
Autores principales: Boezio, Giulia LM, Bensimon-Brito, Anabela, Piesker, Janett, Guenther, Stefan, Helker, Christian SM, Stainier, Didier YR
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524555/
https://www.ncbi.nlm.nih.gov/pubmed/32990594
http://dx.doi.org/10.7554/eLife.57603

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524555/
https://www.ncbi.nlm.nih.gov/pubmed/32990594
http://dx.doi.org/10.7554/eLife.57603

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