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Endothelial TGF-β signaling instructs smooth muscle cell development in the cardiac outflow tract
The development of the cardiac outflow tract (OFT), which connects the heart to the great arteries, relies on a complex crosstalk between endothelial (ECs) and smooth muscle (SMCs) cells. Defects in OFT development can lead to severe malformations, including aortic aneurysms, which are frequently as...
Autores principales: | Boezio, Giulia LM, Bensimon-Brito, Anabela, Piesker, Janett, Guenther, Stefan, Helker, Christian SM, Stainier, Didier YR |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524555/ https://www.ncbi.nlm.nih.gov/pubmed/32990594 http://dx.doi.org/10.7554/eLife.57603 |
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