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Excess centrosomes disrupt vascular lumenization and endothelial cell adherens junctions
Proper blood vessel formation requires coordinated changes in endothelial cell polarity and rearrangement of cell–cell junctions to form a functional lumen. One important regulator of cell polarity is the centrosome, which acts as a microtubule organizing center. Excess centrosomes perturb aspects o...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524686/ https://www.ncbi.nlm.nih.gov/pubmed/32699963 http://dx.doi.org/10.1007/s10456-020-09737-7 |