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Excess centrosomes disrupt vascular lumenization and endothelial cell adherens junctions

Proper blood vessel formation requires coordinated changes in endothelial cell polarity and rearrangement of cell–cell junctions to form a functional lumen. One important regulator of cell polarity is the centrosome, which acts as a microtubule organizing center. Excess centrosomes perturb aspects o...

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Detalles Bibliográficos
Autores principales: Buglak, Danielle B., Kushner, Erich J., Marvin, Allison P., Davis, Katy L., Bautch, Victoria L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524686/
https://www.ncbi.nlm.nih.gov/pubmed/32699963
http://dx.doi.org/10.1007/s10456-020-09737-7