RNA-cDNA hybrids mediate transposition via different mechanisms

Retrotransposons can represent half of eukaryotic genomes. Retrotransposon dysregulation destabilizes genomes and has been linked to various human diseases. Emerging regulators of retromobility include RNA–DNA hybrid-containing structures known as R-loops. Accumulation of these structures at the tra...

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Detalles Bibliográficos
Autores principales: Todd, Lauren A., Hall, Amanda C., Pietrobon, Violena, Chan, Janet N. Y., Laflamme, Guillaume, Mekhail, Karim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524711/
https://www.ncbi.nlm.nih.gov/pubmed/32994470
http://dx.doi.org/10.1038/s41598-020-73018-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524711/
https://www.ncbi.nlm.nih.gov/pubmed/32994470
http://dx.doi.org/10.1038/s41598-020-73018-y

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