Decrease of T-cells exhaustion markers programmed cell death-1 and T-cell immunoglobulin and mucin domain-containing protein 3 and plasma IL-10 levels after successful treatment of chronic hepatitis C

During chronic hepatitis C virus (HCV) infection, both CD4(+) and CD8(+) T-cells become functionally exhausted, which is reflected by increased expression of programmed cell death-1 (PD-1) and T-cell immunoglobulin and mucin domain-containing protein 3 (Tim-3), and elevated anti-inflammatory interle...

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Detalles Bibliográficos
Autores principales: Osuch, Sylwia, Laskus, Tomasz, Berak, Hanna, Perlejewski, Karol, Metzner, Karin J., Paciorek, Marcin, Radkowski, Marek, Caraballo Cortés, Kamila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524731/
https://www.ncbi.nlm.nih.gov/pubmed/32994477
http://dx.doi.org/10.1038/s41598-020-73137-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524731/
https://www.ncbi.nlm.nih.gov/pubmed/32994477
http://dx.doi.org/10.1038/s41598-020-73137-6

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