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Hyaluronan-carnosine conjugates inhibit Aβ aggregation and toxicity

Alzheimer’s disease is the most common neurodegenerative disorder. Finding a pharmacological approach that cures and/or prevents the onset of this devastating disease represents an important challenge for researchers. According to the amyloid cascade hypothesis, increases in extracellular amyloid-β...

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Detalles Bibliográficos
Autores principales: Greco, Valentina, Naletova, Irina, Ahmed, Ikhlas M. M., Vaccaro, Susanna, Messina, Luciano, La Mendola, Diego, Bellia, Francesco, Sciuto, Sebastiano, Satriano, Cristina, Rizzarelli, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524733/
https://www.ncbi.nlm.nih.gov/pubmed/32994475
http://dx.doi.org/10.1038/s41598-020-72989-2