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Stress fiber anisotropy contributes to force-mode dependent chromatin stretching and gene upregulation in living cells

Living cells and tissues experience various complex modes of forces that are important in physiology and disease. However, how different force modes impact gene expression is elusive. Here we apply local forces of different modes via a magnetic bead bound to the integrins on a cell and quantified ce...

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Detalles Bibliográficos
Autores principales: Wei, Fuxiang, Xu, Xiangyu, Zhang, Cunyu, Liao, Yawen, Ji, Baohua, Wang, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524734/
https://www.ncbi.nlm.nih.gov/pubmed/32994402
http://dx.doi.org/10.1038/s41467-020-18584-5