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Stress fiber anisotropy contributes to force-mode dependent chromatin stretching and gene upregulation in living cells
Living cells and tissues experience various complex modes of forces that are important in physiology and disease. However, how different force modes impact gene expression is elusive. Here we apply local forces of different modes via a magnetic bead bound to the integrins on a cell and quantified ce...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524734/ https://www.ncbi.nlm.nih.gov/pubmed/32994402 http://dx.doi.org/10.1038/s41467-020-18584-5 |