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Quantitative analysis of global protein stability rates in tissues

Protein degradation is an essential mechanism for maintaining proteostasis in response to internal and external perturbations. Disruption of this process is implicated in many human diseases. We present a new technique, QUAD (Quantification of Azidohomoalanine Degradation), to analyze the global deg...

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Detalles Bibliográficos
Autores principales: McClatchy, Daniel B., Martínez-Bartolomé, Salvador, Gao, Yu, Lavallée-Adam, Mathieu, Yates, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524747/
https://www.ncbi.nlm.nih.gov/pubmed/32994440
http://dx.doi.org/10.1038/s41598-020-72410-y