Re-establishment of the epigenetic state and rescue of kinome deregulation in Ts65Dn mice upon treatment with green tea extract and environmental enrichment

Down syndrome (DS) is the main genetic cause of intellectual disability due to triplication of human chromosome 21 (HSA21). Although there is no treatment for intellectual disability, environmental enrichment (EE) and the administration of green tea extracts containing epigallocatechin-3-gallate (EG...

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Detalles Bibliográficos
Autores principales: De Toma, I., Ortega, M., Catuara-Solarz, S., Sierra, C., Sabidó, E., Dierssen, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524756/
https://www.ncbi.nlm.nih.gov/pubmed/32994493
http://dx.doi.org/10.1038/s41598-020-72625-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524756/
https://www.ncbi.nlm.nih.gov/pubmed/32994493
http://dx.doi.org/10.1038/s41598-020-72625-z

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